ARAF Antikörper (Middle Region)

Produktnummer ABIN2785788

Produktdetails anti-ARAF Antikörper

Target: ARAF (V-Raf Murine Sarcoma 3611 Viral Oncogene Homolog (ARAF))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Schaf, Hund, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARAF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PRGSPSPASV SSGRKSPHSK SPAEQRERKS LADDKKKVKN LGYRDSGYYW

Homologie: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ARAF. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ARAF

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 606 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ARAF

Target: ARAF (V-Raf Murine Sarcoma 3611 Viral Oncogene Homolog (ARAF))

Andere Bezeichnung: ARAF (ARAF Produkte)

Synonyme: zgc:92074 antikoerper, wu:fk45h07 antikoerper, ARAF antikoerper, a-raf antikoerper, araf antikoerper, araf1 antikoerper, pks2 antikoerper, rafa1 antikoerper, A-RAF antikoerper, ARAF1 antikoerper, PKS2 antikoerper, RAFA1 antikoerper, 1200013E08Rik antikoerper, A-Raf antikoerper, AW495444 antikoerper, Araf1 antikoerper, A-Raf proto-oncogene, serine/threonine kinase antikoerper, A-Raf proto-oncogene, serine/threonine kinase L homeolog antikoerper, A-Raf proto-oncogene, serine/threonine kinase S homeolog antikoerper, Araf proto-oncogene, serine/threonine kinase antikoerper, araf antikoerper, ARAF antikoerper, araf.L antikoerper, araf.S antikoerper, Araf antikoerper

Hintergrund: ARAF belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily. It contains 1 phorbol-ester/DAG-type zinc finger, 1 protein kinase domain, and 1 RBD (Ras-binding) domain. ARAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus.
Alias Symbols: A-RAF, ARAF1, PKS2, RAFA1
Protein Interaction Partner: AGTRAP, KRAS, CDC37, MAP2K1, GNA12, FKBP5, UBC, RNF2, FBXO6, YWHAB, HIPK4, YWHAE, RRAS2, BAD, TEKT4P2, WNK1, NELFCD, DIDO1, TESK1, MAP2K2, MLH1, HSP90AA1, E2F6, BRAF, TIRAP, IRF7, IRAK2, YWHAG, MYO18A, CHD6, YWHAZ, PBK, NUDT14, KLHL12, COPS3, TIMM44, ASS1
Protein Size: 606

Molekulargewicht: 67 kDa

Gen-ID: 369

NCBI Accession: NM_001654, NP_001645

UniProt: P10398

Pathways: MAPK Signalweg, RTK Signalweg, Hepatitis C