Crossover junction endonuclease EME1 (EME1) (N-Term) Antikörper
Kurzübersicht für Crossover junction endonuclease EME1 (EME1) (N-Term) Antikörper (ABIN2785183)
Target
Alle Crossover junction endonuclease EME1 (EME1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- EME1 Antibody - N-terminal region
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Sequenz
- MALKKSSPSL DSGDSDSEEL PTFAFLKKEP SSTKRRQPER EEKIVVVDIS
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Homologie
- Cow: 85%, Dog: 93%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against EME1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human EME1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52987-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Crossover junction endonuclease EME1 (EME1)
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Andere Bezeichnung
- EME1
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Hintergrund
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Background Information: EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication.EME1 and MUS81 (MIM 606591) form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003 [PubMed 14609959]).[supplied by OMIM].
Gene Name: Essential meiotic endonuclease 1 homolog 1 (S. pombe)
Alternative Symbols: MMS4L, SLX2A
Protein Name: Crossover junction endonuclease EME1
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Molekulargewicht
- 63kDa
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Gen-ID
- 146956
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NCBI Accession
- NP_689676
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UniProt
- Q96AY2
Target
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