MAP1LC3A Antikörper (N-Term)

Produktnummer ABIN2784522

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MAP1LC3A in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd und Hund.Es wurde in 1 Publikation zitiert.

Kurzübersicht für MAP1LC3A Antikörper (N-Term) (ABIN2784522)

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP1LC3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MAP1LC3A Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MAP1LC3A Antibody - N-terminal region

Sequenz: MKMRFFSSPC GKAAVDPADR CKEVQQIRDQ HPSKIPVIIE RYKGEKQLPV

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against MAP1LC3A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP1LC3A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51335-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MAP1LC3A Antikörper (ABIN2784522)

Taylor, Kirkegaard: "Modification of cellular autophagy protein LC3 by poliovirus." in: Journal of virology, Vol. 81, Issue 22, pp. 12543-53, (2007) (PubMed).

Details zu MAP1LC3A

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Andere Bezeichnung: MAP1LC3A

Hintergrund:

Background Information: MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3A is one of the light chain subunits and can associate with either MAP1A or MAP1B.MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Microtubule-associated protein 1 light chain 3 alpha

Alternative Symbols: LC3, LC3A, ATG8E, MAP1ALC3, MAP1BLC3

Protein Name: Microtubule-associated proteins 1A/1B light chain 3A

Molekulargewicht: 14kDa

Gen-ID: 84557

NCBI Accession: NP_852610

UniProt: Q9H492

Pathways: Autophagie