PLK1 Antikörper (C-Term)

Produktnummer ABIN2782496

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PLK1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen und Pferd.

Kurzübersicht für PLK1 Antikörper (C-Term) (ABIN2782496)

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PLK1 Antikörper

Bindungsspezifität: C-Term

Sequenz: KRDFRTYRLS LLEEYGCCKE LASRLRYART MVDKLLSSRS ASNRLKAS

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PLK1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PLK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 603 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PLK1

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Andere Bezeichnung: PLK1

Hintergrund: Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis.
Alias Symbols: PLK, STPK13
Protein Interaction Partner: RAP1GAP, CHFR, KLHL22, BRCA1, BORA, EGFR, UBC, NUAK1, MUS81, FBXO6, PPP6R2, STK3, BUB1B, FZR1, CDC20, CHEK2, TP53BP1, CDCA5, LATS1, CENPU, CDC25C, KLHL21, OFD1, CUL2, Sugt1, KRBA1, HSPA4, PHC2, KLHL9, FLJ20712, RABAC1, TANK, RBX1, VCP, CDH1, APP, STAG2, N
Protein Size: 603

Molekulargewicht: 68 kDa

Gen-ID: 5347

NCBI Accession: NM_005030, NP_005021

UniProt: P53350

Pathways: Zellzyklus, M Phase