PLK1 Antikörper (C-Term)

Produktnummer ABIN2782496

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PLK1 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen und Pferd.

Kurzübersicht für PLK1 Antikörper (C-Term) (ABIN2782496)

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PLK1 Antikörper

Bindungsspezifität: C-Term

Sequenz: KRDFRTYRLS LLEEYGCCKE LASRLRYART MVDKLLSSRS ASNRLKAS

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PLK1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PLK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 603 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PLK1

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Andere Bezeichnung: PLK1

Hintergrund: Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis.
Alias Symbols: PLK, STPK13
Protein Interaction Partner: RAP1GAP, CHFR, KLHL22, BRCA1, BORA, EGFR, UBC, NUAK1, MUS81, FBXO6, PPP6R2, STK3, BUB1B, FZR1, CDC20, CHEK2, TP53BP1, CDCA5, LATS1, CENPU, CDC25C, KLHL21, OFD1, CUL2, Sugt1, KRBA1, HSPA4, PHC2, KLHL9, FLJ20712, RABAC1, TANK, RBX1, VCP, CDH1, APP, STAG2, N
Protein Size: 603

Molekulargewicht: 68 kDa

Gen-ID: 5347

NCBI Accession: NM_005030, NP_005021

UniProt: P53350

Pathways: Zellzyklus, M Phase