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IRF7 Antikörper (N-Term)

Dieses Anti-IRF7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IRF7 in WB. Geeignet für Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio), Pferd, Rind (Kuh) und Kaninchen.
Produktnummer ABIN2780566

Kurzübersicht für IRF7 Antikörper (N-Term) (ABIN2780566)

Target

Alle IRF7 Antikörper anzeigen
IRF7 (Interferon Regulatory Factor 7 (IRF7))

Reaktivität

  • 80
  • 56
  • 55
  • 16
  • 7
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio), Pferd, Rind (Kuh), Kaninchen

Wirt

  • 70
  • 11
Kaninchen

Klonalität

  • 58
  • 23
Polyklonal

Konjugat

  • 27
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser IRF7 Antikörper ist unkonjugiert

Applikation

  • 51
  • 22
  • 20
  • 14
  • 14
  • 13
  • 6
  • 6
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 16
    • 16
    • 15
    • 11
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    ISSGCYEGLQ WLDEARTCFR VPWKHFARKD LSEADARIFK AWAVARGRWP

    Homologie

    Cow: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 75%

    Produktmerkmale

    This is a rabbit polyclonal antibody against IRF7. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human IRF7
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 164 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    IRF7 (Interferon Regulatory Factor 7 (IRF7))

    Andere Bezeichnung

    IRF7

    Hintergrund

    IRF7 is interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue.IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.
    Alias Symbols: IRF-7H, IRF7A
    Protein Interaction Partner: UBC, SUMO2, SUMO3, TRAF6, NMI, DEAF1, MAFB, SMAD4, SMAD3, SMAD2, vIRF-1, Dlg4, PIAS4, INSR, GCLM, ACADS, MAVS, IRF7, IRF3, IRAK1, TBK1, TRIM28, SUMO1, EP300, CREBBP, TNFAIP3, TRIM21, P4HA1, ARAF, Gbp4, HACE1, CCDC47, TRMT61B, PALD1, TRMT2A, LTN1, TLK2, IQ
    Protein Size: 164

    Molekulargewicht

    18 kDa

    Gen-ID

    3665

    NCBI Accession

    NM_004031, NP_004022

    Pathways

    TLR Signalweg, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagie
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