FOXO1 Antikörper (N-Term)

Produktnummer ABIN2780391

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FOXO1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Schwein, Hund und Saccharomyces cerevisiae.Es wurde in 1 Publikation zitiert.

Kurzübersicht für FOXO1 Antikörper (N-Term) (ABIN2780391)

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Hund, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FOXO1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FOXO1A Antibody - N-terminal region

Sequenz: MAEAPQVVEI DPDFEPLPRP RSCTWPLPRP EFSQSNSATS SPAPSGSAAA

Homologie: Cow: 92%, Dog: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rat: 85%, Yeast: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXO1A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FOXO1A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100917

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FOXO1 Antikörper (ABIN2780391)

Hsu, Hu: "Energy-regulated molecules maintain young status in the trophocytes and fat cells of old queen honeybees." in: Biogerontology, Vol. 15, Issue 4, pp. 389-400, (2014) (PubMed).

Details zu FOXO1

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Andere Bezeichnung: FOXO1A

Hintergrund:

Background Information: FOXO1A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of FOXO1A has not yet been determined, however, it may play a role in myogenic growth and differentiation. Translocation of FOXO1A gene with PAX3 has been associated with alveolar rhabdomyosarcoma.

Gene Name: Forkhead box O1

Alternative Symbols: FKH1, FKHR, FOXO1A

Protein Name: Forkhead box protein O1

Molekulargewicht: 70kDa

Gen-ID: 2308

NCBI Accession: NP_002006

UniProt: Q12778

Pathways: PI3K-Akt Signalweg, Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling