CHEK1 Antikörper (Middle Region)
Kurzübersicht für CHEK1 Antikörper (Middle Region) (ABIN2779738)
Target
Alle CHEK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- CHEK1 Antibody - middle region
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Sequenz
- WSCGIVLTAM LAGELPWDQP SDSCQEYSDW KEKKTYLNPW KKIDSAPLAL
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CHEK1. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CHEK1
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anti-Checkpoint Kinase 1 (CHEK1) (pSer345) antibody
CHEK1 Reaktivität: Human WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (Middle Region) antibodyCHEK1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibodyCHEK1 Reaktivität: Human WB, IHC (p), DB Wirt: Kaninchen Polyclonal RB7845-RB18425 unconjugated
anti-Checkpoint Kinase 1 (CHEK1) antibodyCHEK1 Reaktivität: Human, Maus WB, ELISA Wirt: Maus Monoclonal 2G1D5 unconjugated
anti-Checkpoint Kinase 1 (CHEK1) (pSer296) antibodyCHEK1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Checkpoint Kinase 1 (CHEK1) antibodyCHEK1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Monoclonal 2F2 unconjugated Recombinant Antibody
anti-Checkpoint Kinase 1 (CHEK1) antibodyKD Validated CHEK1 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 25GB2890 unconjugated Recombinant Antibody
anti-Checkpoint Kinase 1 (CHEK1) (pSer280) antibodyKD Validated CHEK1 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 25GB3390 unconjugated Recombinant Antibody
anti-Checkpoint Kinase 1 (CHEK1) antibodyKD Validated CHEK1 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 25GB2815 unconjugated Recombinant Antibody
anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibodyCHEK1 Reaktivität: Human IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096839
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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Andere Bezeichnung
- CHEK1
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Hintergrund
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Background Information: CHEK1 is required during normal S phase to avoid aberrantly increased initiation of DNA replication, thereby protecting against DNA breakage. Its expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.
Gene Name: Checkpoint kinase 1
Alternative Symbols: CHK1
Protein Name: Serine/threonine-protein kinase Chk1
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Molekulargewicht
- 54kDa
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Gen-ID
- 1111
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NCBI Accession
- NP_001265
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UniProt
- O14757
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Pathways
- p53 Signalweg, Apoptose, Zellzyklus, DNA Reparatur
Target
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