CDK2 Antikörper (Middle Region)

Produktnummer ABIN2779325

Produktdetails anti-CDK2 Antikörper

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schaf, Zebrafisch (Danio rerio), Ziege, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: VLHRDLKPQN LLINTEGAIK LADFGLARAF GVPVRTYTHE VVTLWYRAPE

Homologie: Cow: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CDK2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 298 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CDK2 Antikörper (ABIN2779325)

Huang, Chen, Wu, Huang, He, Tang, Wang, Wang: "The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1α and functions in cellular adaptations." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 4901-13, (2015) (PubMed).

Details zu CDK2

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Andere Bezeichnung: CDK2 (CDK2 Produkte)

Synonyme: p33(CDK2) antikoerper, A630093N05Rik antikoerper, wu:fa10c02 antikoerper, zgc:56598 antikoerper, zgc:77684 antikoerper, eg1 antikoerper, CDKN2 antikoerper, cdk2L antikoerper, cyclin dependent kinase 2 antikoerper, cyclin-dependent kinase 2 antikoerper, cyclin-dependent kinase 2 S homeolog antikoerper, CDK2 antikoerper, Cdk2 antikoerper, cdk2 antikoerper, cdk2.S antikoerper

Hintergrund: Phospho-cdk2 (Thr160) probably involved in the control of the cell cycle. It interacts with cyclins A, D, or E. Activity of cdk2 is maximal during S phase and G2.
Alias Symbols: p33(CDK2)
Protein Interaction Partner: MAPT, CDKN1A, CCNA2, VCP, SAMHD1, IMPDH2, CDK2, SKP1, FZR1, CKS2, CKS1B, CCNE2, GOLGA2, CREBBP, CDKN1C, CDKN1B, CCNE1, CDK13, SKP2, RBL2, RBL1, CCNB1, COPS5, PTMA, HIST1H1A, PRDX1, CCNJ, CDK7, CDK3, EP300, ATP1A1, MYBL2, MNAT1, HSPD1, HSP90AB1, HSP90AA1,
Protein Size: 298

Molekulargewicht: 34 kDa

Gen-ID: 1017

NCBI Accession: NM_001798, NP_001789

UniProt: P24941

Pathways: PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA