CDK2 Antikörper (Middle Region)
Kurzübersicht für CDK2 Antikörper (Middle Region) (ABIN2779325)
Target
Alle CDK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- VLHRDLKPQN LLINTEGAIK LADFGLARAF GVPVRTYTHE VVTLWYRAPE
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Homologie
- Cow: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CDK2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 298 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1α and functions in cellular adaptations." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 4901-13, (2015) (PubMed).
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: "The zebrafish miR-462/miR-731 cluster is induced under hypoxic stress via hypoxia-inducible factor 1α and functions in cellular adaptations." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 4901-13, (2015) (PubMed).
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- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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Andere Bezeichnung
- CDK2
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Hintergrund
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Phospho-cdk2 (Thr160) probably involved in the control of the cell cycle. It interacts with cyclins A, D, or E. Activity of cdk2 is maximal during S phase and G2.
Alias Symbols: p33(CDK2)
Protein Interaction Partner: MAPT, CDKN1A, CCNA2, VCP, SAMHD1, IMPDH2, CDK2, SKP1, FZR1, CKS2, CKS1B, CCNE2, GOLGA2, CREBBP, CDKN1C, CDKN1B, CCNE1, CDK13, SKP2, RBL2, RBL1, CCNB1, COPS5, PTMA, HIST1H1A, PRDX1, CCNJ, CDK7, CDK3, EP300, ATP1A1, MYBL2, MNAT1, HSPD1, HSP90AB1, HSP90AA1,
Protein Size: 298 -
Molekulargewicht
- 34 kDa
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Gen-ID
- 1017
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NCBI Accession
- NM_001798, NP_001789
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UniProt
- P24941
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Pathways
- PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
Target
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