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Kdm6b Antikörper (Middle Region)

Kdm6b Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2778611
  • Target Alle Kdm6b Antikörper anzeigen
    Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
    Bindungsspezifität
    • 12
    • 12
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 50
    • 22
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Schwein
    Wirt
    • 54
    • 1
    • 1
    Kaninchen
    Klonalität
    • 55
    • 1
    Polyklonal
    Konjugat
    • 29
    • 6
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Kdm6b Antikörper ist unkonjugiert
    Applikation
    • 44
    • 31
    • 15
    • 11
    • 6
    • 5
    • 3
    Western Blotting (WB)
    Sequenz
    AGLQGVVVLE QYRTEELAQA YDAFTLVRAR RARGQRRRAL GQAAGTGFGS
    Homologie
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against JMJD3. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human JMJD3
    Top Product
    Discover our top product Kdm6b Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 644 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
    Andere Bezeichnung
    JMJD3 (Kdm6b Produkte)
    Synonyme
    jmjd3 antikoerper, kdm6b antikoerper, si:ch211-237l4.7 antikoerper, 1700064E03Rik antikoerper, BC038313 antikoerper, Jmjd3 antikoerper, mKIAA0346 antikoerper, JMJD3 antikoerper, lysine (K)-specific demethylase 6B antikoerper, lysine demethylase 6B antikoerper, lysine (K)-specific demethylase 6B, b antikoerper, KDM1 lysine (K)-specific demethylase 6B antikoerper, kdm6b antikoerper, KDM6B antikoerper, kdm6bb antikoerper, Kdm6b antikoerper
    Hintergrund
    JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
    Alias Symbols: KIAA0346, JMJD3
    Protein Interaction Partner: WDR5, ASH2L, RBBP5, UBC, TK1, CSNK2B, HIST1H3A, WAS, SMAD3, SMAD2, SMAD4, SMAD1,
    Protein Size: 1643
    Molekulargewicht
    177 kDa
    Gen-ID
    23135
    NCBI Accession
    NM_001080424
    UniProt
    O15054
    Pathways
    Warburg Effekt
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