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Kdm6b Antikörper (AA 954-987)

Kdm6b Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB10080 unconjugated
Produktnummer ABIN387864
  • Target Alle Kdm6b Antikörper anzeigen
    Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
    Bindungsspezifität
    • 12
    • 12
    • 6
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 954-987
    Reaktivität
    • 50
    • 22
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 54
    • 1
    • 1
    Kaninchen
    Klonalität
    • 55
    • 1
    Polyklonal
    Konjugat
    • 29
    • 6
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Kdm6b Antikörper ist unkonjugiert
    Applikation
    • 44
    • 31
    • 15
    • 11
    • 6
    • 5
    • 3
    Western Blotting (WB)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This Mouse JMJD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 954-987 amino acids from the Central region of mouse JMJD3.
    Klon
    RB10080
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product Kdm6b Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Shaw, Martin: "Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes." in: EMBO reports, Vol. 10, Issue 8, pp. 881-6, (2009) (PubMed).

  • Target
    Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
    Andere Bezeichnung
    JMJD3 (Kdm6b Produkte)
    Synonyme
    jmjd3 antikoerper, kdm6b antikoerper, si:ch211-237l4.7 antikoerper, 1700064E03Rik antikoerper, BC038313 antikoerper, Jmjd3 antikoerper, mKIAA0346 antikoerper, JMJD3 antikoerper, lysine (K)-specific demethylase 6B antikoerper, lysine demethylase 6B antikoerper, lysine (K)-specific demethylase 6B, b antikoerper, KDM1 lysine (K)-specific demethylase 6B antikoerper, kdm6b antikoerper, KDM6B antikoerper, kdm6bb antikoerper, Kdm6b antikoerper
    Hintergrund
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
    Molekulargewicht
    176355
    Gen-ID
    216850
    NCBI Accession
    NP_001017426
    UniProt
    Q5NCY0
    Pathways
    Warburg Effekt
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