Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PDK4 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PDK4 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Rind (Kuh), Hund und Meerschweinchen und wurde in 1 Publikation erwähnt.
Produktnummer ABIN2777592

Kurzübersicht für PDK4 Antikörper (N-Term) (ABIN2777592)

Target

Alle PDK4 Antikörper anzeigen
PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Reaktivität

Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Rind (Kuh), Hund, Meerschweinchen

Wirt

  • 71
  • 13
Kaninchen

Klonalität

  • 75
  • 11
Polyklonal

Konjugat

  • 48
  • 7
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PDK4 Antikörper ist unkonjugiert

Applikation

  • 70
  • 41
  • 29
  • 13
  • 13
  • 9
  • 9
  • 8
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 9
    • 8
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    MKAARFVLRS AGSLNGAGLV PREVEHFSRY SPSPLSMKQL LDFGSENACE

    Homologie

    Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%

    Produktmerkmale

    This is a rabbit polyclonal antibody against PDK4. It was validated on Western Blot and immunohistochemistry.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human PDK4
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 411 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

  • Target

    PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

    Andere Bezeichnung

    PDK4

    Hintergrund

    PDK4 is a member of the PDK/BCKDK protein kinase family and is a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism.This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
    Alias Symbols: FLJ40832
    Protein Interaction Partner: UBC, DLAT, PDK4, PDHA1, TRIM63,
    Protein Size: 411

    Molekulargewicht

    46 kDa

    Gen-ID

    5166

    NCBI Accession

    NM_002612, NP_002603

    UniProt

    Q16654

    Pathways

    PI3K-Akt Signalweg, Hedgehog Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
Sie sind hier:
Chat with us!