KAP1 Antikörper (N-Term)

Produktnummer ABIN2777312

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KAP1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund und Rind (Kuh).

Kurzübersicht für KAP1 Antikörper (N-Term) (ABIN2777312)

Target: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KAP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: AASAAAASAA AASAASGSPG PGEGSAGGEK RSTAPSAAAS ASASAAASSP

Homologie: Cow: 92%, Dog: 100%, Human: 100%, Mouse: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIM28. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM28

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 835 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KAP1

Target: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Andere Bezeichnung: TRIM28

Hintergrund: TRIM28 mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. TRIM28 localizes to the nucleus and is thought to associate with specific chromatin regions. It is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING,a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ29029, KAP1, RNF96, TF1B, TIF1B
Protein Interaction Partner: WWOX, ERLIN2, HUWE1, SUMO1, UBC, SPRTN, SENP7, HAUS2, MAGEC2, CBX5, WHSC1, UBE2I, AURKA, SUMO2, SUMO3, RNF4, CEP250, TRIM28, HIF1A, CHD3, ATM, ZNF350, STAU1, HIST3H3, LYN, NEDD8, MDM2, ZBTB1, RPA3, RPA2, RPA1, RNF2, SUZ12, EZH2, BMI1, EED, BRCC3, WRNIP1,
Protein Size: 835

Molekulargewicht: 88 kDa

Gen-ID: 10155

NCBI Accession: NM_005762, NP_005753

UniProt: Q13263

Pathways: Hedgehog Signalweg, Positive Regulation of Response to DNA Damage Stimulus