Glucagon Antikörper (N-Term)
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- Target Alle Glucagon (GCG) Antikörper anzeigen
- Glucagon (GCG)
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Maus, Rind (Kuh), Hund, Schaf, Meerschweinchen, Kaninchen, Pferd, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Glucagon Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LSDPDQMNED KRHSQGTFTS DYSKYLDSRR AQDFVQWLMN TKRNRNNIAK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 75%
- Produktmerkmale
- This is a rabbit polyclonal antibody against GCG. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human GCG
- Top Product
- Discover our top product GCG Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 180 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Glucagon (GCG)
- Andere Bezeichnung
- GCG (GCG Produkte)
- Synonyme
- GLP1 antikoerper, GLP2 antikoerper, GRPP antikoerper, GLP-1 antikoerper, Glu antikoerper, PPG antikoerper, GCG antikoerper, gcg-A antikoerper, gcg1 antikoerper, glucagon antikoerper, glucagon L homeolog antikoerper, GCG antikoerper, Gcg antikoerper, gcg.L antikoerper
- Hintergrund
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GCG is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Alias Symbols: GLP1, GLP2, GRPP
Protein Interaction Partner: ARRB2, GLP1R, GLP2R, MEP1B, MEP1A, GCGR, CTSL, CPE,
Protein Size: 180 - Molekulargewicht
- 20 kDa
- Gen-ID
- 2641
- NCBI Accession
- NM_002054, NP_002045
- UniProt
- P01275
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
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