Growth Hormone 1 Antikörper (C-Term)

Produktnummer ABIN2776980

Der Kaninchen Polyklonal Anti-Growth Hormone 1-Antikörper wurde für WB validiert. Er ist geeignet, Growth Hormone 1 in Proben von Human, Ratte, Maus, Schwein, Rind (Kuh), Pferd, Schaf, Ziege und Kaninchen zu detektieren.

Kurzübersicht für Growth Hormone 1 Antikörper (C-Term) (ABIN2776980)

Target: Growth Hormone 1 (GH1)

Reaktivität: Human, Ratte, Maus, Schwein, Rind (Kuh), Pferd, Schaf, Ziege, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Growth Hormone 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Growth Hormone 1 Antikörper

Bindungsspezifität: C-Term

Sequenz: TYSKFDTNSH NDDALLKNYG LLYCFRKDMD KVETFLRIVQ CRSVEGSCGF

Homologie: Cow: 100%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GH1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 177 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Andere Bezeichnung: GH1

Hintergrund: The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
Alias Symbols: GH, GH-N, GHN, IGHD1B, hGH-N
Protein Interaction Partner: GHR, BAG3, BTRC, PRLR, GH1, SHC1, STRAP, LTA4H,
Protein Size: 177

Molekulargewicht: 20 kDa

Gen-ID: 2688

NCBI Accession: NM_022560, NP_072054

UniProt: A6NEF6

Pathways: NF-kappaB Signalweg, JAK-STAT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process