Hepcidin Antikörper (N-Term)

Produktnummer ABIN2776909

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Hepcidin in WB. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.Es wurde in 1 Publikation zitiert.

Kurzübersicht für Hepcidin Antikörper (N-Term) (ABIN2776909)

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hepcidin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Hepcidin Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: HAMP Antibody - N-terminal region

Sequenz: MALSSQIWAA CLLLLLLLAS LTSGSVFPQQ TGQLAELQPQ DRAGARASWM

Homologie: Human: 100%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against HAMP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HAMP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41620-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Hepcidin Antikörper (ABIN2776909)

Theurl, Theurl, Seifert, Mair, Nairz, Rumpold, Zoller, Bellmann-Weiler, Niederegger, Talasz, Weiss: "Autocrine formation of hepcidin induces iron retention in human monocytes." in: Blood, Vol. 111, Issue 4, pp. 2392-9, (2008) (PubMed).

Details zu Hepcidin

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Andere Bezeichnung: HAMP

Hintergrund:

Background Information: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature p

Gene Name: Hepcidin antimicrobial peptide

Alternative Symbols: HEPC, PLTR, HFE2B, LEAP1

Protein Name: Hepcidin

Molekulargewicht: 9kDa

Gen-ID: 57817

NCBI Accession: NP_066998

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis