MCM5 Antikörper (N-Term)

Produktnummer ABIN2774889

Produktdetails anti-MCM5 Antikörper

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MSGFDDPGIF YSDSFGGDAQ ADEGQARKSQ LQRRFKEFLR QYRVGTDRTG

Homologie: Cow: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against MCM5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MCM5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 734 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MCM5

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Andere Bezeichnung: MCM5 (MCM5 Produkte)

Synonyme: 23.m06024 antikoerper, cdc46 antikoerper, xmcm5 antikoerper, CDC46 antikoerper, P1-CDC46 antikoerper, Afu5g02520 antikoerper, NCU01171.1 antikoerper, AA617332 antikoerper, AI324988 antikoerper, AL033333 antikoerper, Cdc46 antikoerper, Mcmd5 antikoerper, mCD46 antikoerper, mCDC46 antikoerper, mcm5 antikoerper, wu:fb34a06 antikoerper, CG4082 antikoerper, DmCDC46 antikoerper, DmCDC465 antikoerper, DmMCM5 antikoerper, DmMcm5 antikoerper, DmeMCM5 antikoerper, Dmel\\CG4082 antikoerper, MCM5 antikoerper, McM5 antikoerper, PCR4 antikoerper, DNA replication licensing factor MCM5 antikoerper, minichromosome maintenance complex component 5 S homeolog antikoerper, minichromosome maintenance complex component 5 antikoerper, DNA replication licensing factor Mcm5 antikoerper, DNA replication licensing factor mcm5 antikoerper, MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) antikoerper, minichromosome maintenance complex component 5 L homeolog antikoerper, Minichromosome maintenance 5 antikoerper, DNA replication licensing factor mcm-5 antikoerper, BBOV_IV010040 antikoerper, mcm5.S antikoerper, MCM5 antikoerper, AFUA_5G02520 antikoerper, NCU01171 antikoerper, PVX_084615 antikoerper, LOC5576119 antikoerper, CpipJ_CPIJ008678 antikoerper, Bm1_24480 antikoerper, CMU_022890 antikoerper, Mcm5 antikoerper, mcm5 antikoerper, TP01_0722 antikoerper, mcm5.L antikoerper, mcm-5 antikoerper

Hintergrund: The protein encoded by MCM5 is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
Alias Symbols: CDC46, P1-CDC46
Protein Interaction Partner: KRTAP10-7, RBPMS, SUMO2, SUMO3, MCMBP, UBC, RNF2, NEK9, MCM3, HSP90AB1, HSP90AA1, FKBP5, MAGED2, CAP1, BAG3, CD81, IGSF8, TCEA1, PNKP, VCAM1, ORC5, ORC1, MCM7, MCM2, ITGA4, FN1, CDKN2A, CDC5L, NOTCH1, MYBBP1A, U2AF1, MCM6, MCM4, HNRNPU, APP, FBXO6, NEDD8,
Protein Size: 734

Molekulargewicht: 82 kDa

Gen-ID: 4174

NCBI Accession: NM_006739, NP_006730

UniProt: P33992

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA