MCM5 Antikörper (AA 1-50)
Kurzübersicht für MCM5 Antikörper (AA 1-50) (ABIN7448655)
Target
Alle MCM5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-50
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Verwendungszweck
- Rabbit anti-MCM5 IHC Antibody, Affinity Purified
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Homologie
- X. laevis,Orangutan,Chimpanzee,Northern white-cheeked gibbon
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Aufreinigung
- Affinity Purified
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Immunogen
- Between AA 1 and 50
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Isotyp
- IgG
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Applikationshinweise
- 1:100 - 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 250 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Haltbarkeit
- 12 months
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- MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))
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Andere Bezeichnung
- MCM5
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Hintergrund
- Background: The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM5 can form a subcomplex with MCM3. MCM5 also appears to play a role in transcription. MCM5 has been shown to interact with the signal transducer and activator of transcription 1 (STAT1) and demonstrated to be essential for STAT1 target gene transcription.
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Gen-ID
- 4174
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NCBI Accession
- NP_006730
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UniProt
- P33992
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Pathways
- DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
Target
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