EIF2AK2 Antikörper (Middle Region)
Kurzübersicht für EIF2AK2 Antikörper (Middle Region) (ABIN2774645)
Target
Alle EIF2AK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Middle Region
-
Sequenz
- QVFKAKHRID GKTYVIKRVK YNNEKAEREV KALAKLDHVN IVHYNGCWDG
-
Homologie
- Cow: 92%, Dog: 83%, Horse: 91%, Human: 100%, Mouse: 83%, Pig: 83%, Rabbit: 100%, Rat: 92%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against EIF2AK2. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human EIF2AK2
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 551 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
-
Andere Bezeichnung
- EIF2AK2
-
Hintergrund
-
EIF2AK2 might play a role in ER stress-induced apoptosis and in Alzheimer's disease. Alzheimer cases show prominent EIF2AK2 activation in association with neuritic plaques and pyramidal neurons in the hippocampus and neocortex.
Alias Symbols: EIF2AK1, MGC126524, PKR, PRKR
Protein Interaction Partner: UBC, TRAF6, TRAF5, TRAF2, EGFR, DHX9, STAU2, PRKRA, EIF2AK2, HECW2, TOP1, STAU1, DICER1, DHX30, EBNA1BP2, IGF2BP2, IGF2BP3, PABPC4, MOV10, ILF3, ILF2, HSP90AA1, EIF2A, NOC3L, GNL3, NOP2, HNRNPC, HIST1H1C, ELAVL1, NPM1, IL7R, gag, Jak2, TYK2, JAK1, EIF2S1,
Protein Size: 551 -
Molekulargewicht
- 62 kDa
-
Gen-ID
- 5610
-
NCBI Accession
- NM_002759, NP_002750
-
UniProt
- P19525
-
Pathways
- DNA Reparatur, ER-Nucleus Signaling, Hepatitis C
Target
-