PDGFA Antikörper (C-Term)

Produktnummer ABIN2774382

Dieses Anti-PDGFA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PDGFA in WB. Geeignet für Human, Maus, Ratte, Hund und Meerschweinchen.

Kurzübersicht für PDGFA Antikörper (C-Term) (ABIN2774382)

Target: PDGFA (Platelet Derived Growth Factor A (PDGFA))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDGFA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDGFA Antikörper

Bindungsspezifität: C-Term

Sequenz: HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTDVR

Homologie: Dog: 85%, Guinea Pig: 82%, Human: 100%, Mouse: 85%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against PDGFA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDGFA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDGFA

Target: PDGFA (Platelet Derived Growth Factor A (PDGFA))

Andere Bezeichnung: PDGFA

Hintergrund: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis, knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.
Alias Symbols: PDGF-A, PDGF1
Protein Interaction Partner: COL6A1, COL5A1, COL4A1, COL3A1, COL2A1, COL1A2, COL1A1, PDAP1, DUSP3, SPARC, PDGFRA, PDGFA, HSPG2, FURIN, A2M, PLCG1,
Protein Size: 196

Molekulargewicht: 21 kDa

Gen-ID: 5154

NCBI Accession: NM_033023, NP_148983

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling