PDGFA Antikörper (N-Term)

Produktnummer ABIN388459

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PDGFA in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PDGFA Antikörper (N-Term) (ABIN388459)

Target: PDGFA (Platelet Derived Growth Factor A (PDGFA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDGFA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB01999

Produktdetails anti-PDGFA Antikörper

Bindungsspezifität: AA 60-89, N-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PDGFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human PDGFA.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PDGFA

Target: PDGFA (Platelet Derived Growth Factor A (PDGFA))

Andere Bezeichnung: PDGFA

Hintergrund: PDGFA is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis, knockout mice die either as embryos or shortly after birth.

Molekulargewicht: 24043

Gen-ID: 5154

NCBI Accession: NP_002598, NP_148983

UniProt: P04085

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling