Caspase 6 Antikörper (Middle Region)

Produktnummer ABIN2774243

Der Kaninchen Polyklonal anti-Caspase 6 Antikörper wird verwendet zum Nachweis von Caspase 6 in Proben von Human, Maus und Schwein. Er wurde validiert für WB.

Kurzübersicht für Caspase 6 Antikörper (Middle Region) (ABIN2774243)

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Reaktivität: Human, Maus, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Caspase 6 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: CASP6 Antibody - middle region

Sequenz: QACRGNQHDV PVIPLDVVDN QTEKLDTNIT EVDAASVYTL PAGADFLMCY

Homologie: Human: 100%, Mouse: 82%, Pig: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against CASP6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CASP6

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58994-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Andere Bezeichnung: CASP6

Hintergrund:

Background Information: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.

Gene Name: Caspase 6, apoptosis-related cysteine peptidase

Alternative Symbols: MCH2

Protein Name: Caspase-6

Molekulargewicht: 33kDa

Gen-ID: 839

NCBI Accession: NP_001217

UniProt: P55212

Pathways: Apoptose, Caspase Kaskade in der Apoptose