Caspase 6 Antikörper (Middle Region)

Produktnummer ABIN2774243

Produktdetails anti-Caspase 6 Antikörper

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QACRGNQHDV PVIPLDVVDN QTEKLDTNIT EVDAASVYTL PAGADFLMCY

Homologie: Human: 100%, Mouse: 82%, Pig: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against CASP6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CASP6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 293 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Caspase 6

Target: Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))

Andere Bezeichnung: CASP6 (CASP6 Produkte)

Synonyme: xCaspase-6 antikoerper, mch2 antikoerper, caspase-6 antikoerper, zgc:112960 antikoerper, CASP6 antikoerper, casp6 antikoerper, Mch2 antikoerper, mCASP-6 antikoerper, MCH2 antikoerper, caspase 6 L homeolog antikoerper, caspase 6 antikoerper, caspase 6, apoptosis-related cysteine peptidase antikoerper, group XIIA secretory phospholipase A2 antikoerper, caspase-6 antikoerper, casp6.L antikoerper, casp6 antikoerper, CASP6 antikoerper, CpipJ_CPIJ017008 antikoerper, Casp6 antikoerper

Hintergrund: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.
Alias Symbols: MCH2
Protein Interaction Partner: CASP6, XIAP, CRYAB, UBC, CASP3, RB1, IKBKG, PRKAB2, SP1, COPS6, SATB1, TAB1, MAPK6, PIN1, UBE4A, NUAK1, UBE4B, CHD3, PSME3, EIF2S1, CFLAR, PPL, NEDD4, SRP72, CASP8, CASP10, TRAF1, PSEN2, SRF, VIM, PRKCZ, MAPT, LMNB1, LMNA, KRT18, HTT, TOP1, DSP, PCYT1A, T
Protein Size: 293

Molekulargewicht: 33 kDa

Gen-ID: 839

NCBI Accession: NM_001226, NP_001217

UniProt: P55212

Pathways: Apoptose, Caspase Kaskade in der Apoptose