SETMAR Antikörper (C-Term)

Produktnummer ABIN2773983

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SETMAR in WB. Er zeigt eine Reaktivität gegenüber Human und Rind (Kuh).

Kurzübersicht für SETMAR Antikörper (C-Term) (ABIN2773983)

Target: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Reaktivität: Human, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETMAR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SETMAR Antikörper

Bindungsspezifität: C-Term

Sequenz: FLQGKRFHNQ QDAENAFQEF VESQSTDFYA TGINQLISRW QKCVDCNGSY

Homologie: Cow: 100%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SETMAR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SETMAR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SETMAR

Target: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Andere Bezeichnung: SETMAR

Hintergrund: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain.
Protein Interaction Partner: CHEK1, H3F3C, tat, PRPF19, SETMAR, RAD9A, PCNA, TOP2A, XRCC4,
Protein Size: 545

Molekulargewicht: 59 kDa

Gen-ID: 6419

NCBI Accession: NP_001230652

UniProt: E7EN68

Pathways: Positive Regulation of Response to DNA Damage Stimulus