SETMAR Antikörper

Produktnummer ABIN7262651

Produktdetails anti-SETMAR Antikörper

Target: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETMAR Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human SETMAR (NP_006506.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:20-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SETMAR

Target: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Andere Bezeichnung: SETMAR (SETMAR Produkte)

Synonyme: HsMar1 antikoerper, METNASE antikoerper, Mar1 antikoerper, 5830404F24Rik antikoerper, Etet2 antikoerper, SETMAR antikoerper, zgc:172212 antikoerper, SET domain and mariner transposase fusion gene antikoerper, SET domain without mariner transposase fusion antikoerper, histone-lysine N-methyltransferase SETMAR antikoerper, SETMAR antikoerper, Setmar antikoerper, LOC470738 antikoerper, setmar antikoerper, LOC703880 antikoerper, LOC100447656 antikoerper, LOC100586616 antikoerper

Hintergrund: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

Gen-ID: 6419

UniProt: Q53H47

Pathways: Positive Regulation of Response to DNA Damage Stimulus