SETMAR Antikörper (AA 225-275)

Produktnummer ABIN7451473

Produktdetails anti-SETMAR Antikörper

Target: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Bindungsspezifität: AA 225-275

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETMAR Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Verwendungszweck: Rabbit anti-Metnase Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: Between AA 225 and 275

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu SETMAR

Target: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Andere Bezeichnung: Metnase (SETMAR Produkte)

Synonyme: HsMar1 antikoerper, METNASE antikoerper, Mar1 antikoerper, 5830404F24Rik antikoerper, Etet2 antikoerper, SETMAR antikoerper, zgc:172212 antikoerper, SET domain and mariner transposase fusion gene antikoerper, SET domain without mariner transposase fusion antikoerper, histone-lysine N-methyltransferase SETMAR antikoerper, SETMAR antikoerper, Setmar antikoerper, LOC470738 antikoerper, setmar antikoerper, LOC703880 antikoerper, LOC100447656 antikoerper, LOC100586616 antikoerper

Hintergrund: Background: Metnase is also known as Histone-lysine N-methyltransferase SETMAR. Metnase is a histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Metanase specifically mediates dimethylation of H3 'Lys-36', and has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Metnase possessess DNA nicking activity and in vivo end joining activity, and it may mediate genomic integration of foreign DNA [taken from the Universal Protein Resource (UniProt) Q53H47].

Gen-ID: 6419

UniProt: Q53H47

Pathways: Positive Regulation of Response to DNA Damage Stimulus