SETMAR Antikörper (Internal Region)

Produktnummer ABIN7224234

Der Kaninchen Polyklonal anti-SETMAR Antikörper wird verwendet zum Nachweis von SETMAR in Proben von Human, Maus und Ratte. Er wurde validiert für ELISA, IHC und IF.

Kurzübersicht für SETMAR Antikörper (Internal Region) (ABIN7224234)

Target: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETMAR Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SETMAR Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit Anti-SETMAR Polyclonal Antibody

Spezifität: SETMAR Polyclonal Antibody detects endogenous levels of SETMAR protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human SETMAR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SETMAR

Target: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Andere Bezeichnung: SETMAR

Hintergrund: SETMAR, Histone-lysine N-methyltransferase SETMAR, SET domain and mariner transposase fusion gene-containing protein, HsMar1, MetnaseSETMAR (SET domain and mariner transposase fusion gene) encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. SETMAR exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

Gen-ID: 6419

UniProt: Q53H47

Pathways: Positive Regulation of Response to DNA Damage Stimulus