RAD51 Homolog B Antikörper (AA 119-346)

Produktnummer ABIN2730412

Der Maus Monoklonal Anti-RAD51 Homolog B-Antikörper wurde für WB, IF und FACS validiert. Er ist geeignet, RAD51 Homolog B in Proben von Human zu detektieren.

Kurzübersicht für RAD51 Homolog B Antikörper (AA 119-346) (ABIN2730412)

Target: RAD51 Homolog B (Rad51B)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RAD51 Homolog B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: 7H4

Produktdetails anti-RAD51 Homolog B Antikörper

Bindungsspezifität: AA 119-346

Produktmerkmale: Homo sapiens RAD51 homolog B (S. cerevisiae) (RAD51B), transcript variant 3

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 119-346 of human RAD51L1(NP_598193) produced in E.coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:500, IF 1:100, FLOW 1:100,

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu RAD51 Homolog B

Target: RAD51 Homolog B (Rad51B)

Andere Bezeichnung: RAD51L1

Hintergrund: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.

Molekulargewicht: 42 kDa

Gen-ID: 5890

NCBI Accession: NM_133509

HGNC: 5890

Pathways: DNA Reparatur