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TRAIL Antikörper
TNFSF10
Reaktivität: Human
WB, IF, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-TRAIL Antikörper
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Target
Alle TRAIL (TNFSF10) Antikörper anzeigen
TRAIL (TNFSF10)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
Reaktivität
Alle Reaktivitäten für TRAIL Antikörper
Human
Wirt
Alle Wirte für TRAIL Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für TRAIL Antikörper
Polyklonal
Konjugat
Alle Konjugate für TRAIL Antikörper
Dieser TRAIL Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TRAIL Antikörper
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This TRAIL antibody detects endogenous levels of TRAIL protein. (region surrounding Ser63)
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
Affinity-Chromatography using epitope-specific immunogen
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Discover our top product TNFSF10 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1/20000approx. 1/40000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu TRAIL
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Target
TRAIL (TNFSF10)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
Andere Bezeichnung
CD253 / TRAIL (TNFSF10 Produkte )
Synonyme
APO2L antikoerper, Apo-2L antikoerper, CD253 antikoerper, TL2 antikoerper, TRAIL antikoerper, A330042I21Rik antikoerper, AI448571 antikoerper, APO-2L antikoerper, Ly81 antikoerper, Trail antikoerper, tl2 antikoerper, apo2l antikoerper, cd253 antikoerper, trail antikoerper, apo-2l antikoerper, trail1 antikoerper, xtrail1 antikoerper, tnfsf10l2 antikoerper, zgc:92320 antikoerper, TNLG6A antikoerper, TNF superfamily member 10 antikoerper, tumor necrosis factor (ligand) superfamily, member 10 antikoerper, tumor necrosis factor superfamily member 10 antikoerper, TNF superfamily member 10 S homeolog antikoerper, TNFSF10 antikoerper, Tnfsf10 antikoerper, tnfsf10.S antikoerper, tnfsf10 antikoerper
Hintergrund
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), also referred to as Apo2 ligand, first identified based on its sequence homology to TNF and Fas/Apo ligand is a member of the TNF family of cytokines and either exists as a type II membrane or soluble protein. TRAIL induces apoptosis in a variety of transformed cell lines and plays a role in anti-tumor and anti-viral immune surveillance. TRAIL signals via binding with death receptors DR4 (TRAIL-R1) (4) and DR5 (TRAIL-R2) which can trigger apoptosis as well as NF-κB activation.Synonyms: APO2L, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, TNFSF10, Tumor necrosis factor ligand superfamily member 10
Molekulargewicht
approx. 34 kDa
Gen-ID
8743
NCBI Accession
NP_003801
UniProt
P50591
Pathways
Apoptose , Positive Regulation of Endopeptidase Activity
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