CDK2 Antikörper
-
- Target Alle CDK2 Antikörper anzeigen
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CDK2 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
- Produktmerkmale
- Homo sapiens cyclin-dependent kinase 2 (CDK2), transcript variant 1
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human CDK2 (NP_001789) produced in HEK293T cell.
- Klon
- 1H5
- Isotyp
- IgG2a
- Top Product
- Discover our top product CDK2 Primärantikörper
-
-
- Applikationshinweise
- WB 1:2000, IF 1:100, FLOW 1:100
- Kommentare
-
The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
-
- Target
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
- Andere Bezeichnung
- CDK2 (CDK2 Produkte)
- Hintergrund
- The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.
- Molekulargewicht
- 33.7 kDa
- Gen-ID
- 1017
- NCBI Accession
- NM_001798
- HGNC
- 1017
- Pathways
- PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
-