Kdm6b Antikörper (AA 1028-1684)

Produktnummer ABIN2668350

Dieser Maus Monoklonal Antikörper detektiert spezifisch Kdm6b in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Kdm6b Antikörper (AA 1028-1684) (ABIN2668350)

Target: Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Kdm6b Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 67-A2

Produktdetails anti-Kdm6b Antikörper

Bindungsspezifität: AA 1028-1684

Verwendungszweck: JMJD3 / KDM6B antibody (mAb) (Clone 67-A2)

Aufreinigung: Protein A Chromatography

Immunogen: This antibody was raised against a recombinant protein corresponding to amino acids 1028-1684 of human JMJD3 / KDM6B.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 0.5 - 2 μg/mL dilution

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Lagerung: -20 °C

Informationen zur Lagerung: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Haltbarkeit: 24 months

Details zu Kdm6b

Target: Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

Andere Bezeichnung: JMJD3 / KDM6B

Hintergrund: JMJD3 / KMD6B (Jumonji domain-containing protein 3 lysine (K)-specific demethylase 6B) Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.

Molekulargewicht: 150 kDa

Gen-ID: 23135

NCBI Accession: NP_001073893

Pathways: Warburg Effekt