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SIRT1 Antikörper (AA 581-630)

SIRT1 Reaktivität: Human WB, IP, IF, ICC Wirt: Maus Monoclonal 2G1-F7 unconjugated
Produktnummer ABIN2668278
  • Target Alle SIRT1 Antikörper anzeigen
    SIRT1 (Sirtuin 1 (SIRT1))
    Bindungsspezifität
    • 27
    • 16
    • 16
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 581-630
    Reaktivität
    • 141
    • 88
    • 57
    • 34
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 128
    • 19
    • 2
    • 2
    • 1
    Maus
    Klonalität
    • 112
    • 40
    Monoklonal
    Konjugat
    • 73
    • 14
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Dieser SIRT1 Antikörper ist unkonjugiert
    Applikation
    • 124
    • 50
    • 50
    • 41
    • 39
    • 35
    • 25
    • 22
    • 20
    • 13
    • 9
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Aufreinigung
    Protein G Chromatography
    Immunogen
    This SIRT1 antibody was raised against a synthetic peptide corresponding to amino acids 581-630 of human SIRT1.
    Klon
    2G1-F7
    Isotyp
    IgG1
    Top Product
    Discover our top product SIRT1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 μg/μL
    Buffer
    10 mM sodium phosphate pH 7.5, 150 mM NaCl, 30 % glycerol, 0.035 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    Lagerung
    -20 °C
    Informationen zur Lagerung
    Antibodies in solution can be stored at -20 °C for 2 years.
    Haltbarkeit
    6 months
  • Rajendran, Kidane, Yu, Dashwood, Bisson, Löhr, Ho, Williams, Dashwood: "HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates." in: Epigenetics, Vol. 8, Issue 6, pp. 612-23, (2013) (PubMed).

    Vaquero, Scher, Lee, Erdjument-Bromage, Tempst, Reinberg: "Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin." in: Molecular cell, Vol. 16, Issue 1, pp. 93-105, (2004) (PubMed).

  • Target
    SIRT1 (Sirtuin 1 (SIRT1))
    Andere Bezeichnung
    SIRT1 (SIRT1 Produkte)
    Synonyme
    sirtuin 1 antikoerper, AA673258 antikoerper, SIR2L1 antikoerper, Sir2 antikoerper, Sir2a antikoerper, Sir2alpha antikoerper, sir2l1 antikoerper, sirtuin antikoerper, SIR2 antikoerper, sirtuin 1 antikoerper, sirtuin 1 L homeolog antikoerper, SIRT1 antikoerper, SRT1 antikoerper, Sirt1 antikoerper, sirt1.L antikoerper
    Molekulargewicht
    120 kDa
    Gen-ID
    23411
    Pathways
    MAPK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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