SIRT1 Antikörper (AA 581-630)
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- Target Alle SIRT1 Antikörper anzeigen
- SIRT1 (Sirtuin 1 (SIRT1))
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Bindungsspezifität
- AA 581-630
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SIRT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Aufreinigung
- Protein G Chromatography
- Immunogen
- This SIRT1 antibody was raised against a synthetic peptide corresponding to amino acids 581-630 of human SIRT1.
- Klon
- 2G1-F7
- Isotyp
- IgG1
- Top Product
- Discover our top product SIRT1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 μg/μL
- Buffer
- 10 mM sodium phosphate pH 7.5, 150 mM NaCl, 30 % glycerol, 0.035 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
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Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Antibodies in solution can be stored at -20 °C for 2 years.
- Haltbarkeit
- 6 months
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HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates." in: Epigenetics, Vol. 8, Issue 6, pp. 612-23, (2013) (PubMed).
: "Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin." in: Molecular cell, Vol. 16, Issue 1, pp. 93-105, (2004) (PubMed).
: "
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HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates." in: Epigenetics, Vol. 8, Issue 6, pp. 612-23, (2013) (PubMed).
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- Target
- SIRT1 (Sirtuin 1 (SIRT1))
- Andere Bezeichnung
- SIRT1 (SIRT1 Produkte)
- Molekulargewicht
- 120 kDa
- Gen-ID
- 23411
- Pathways
- MAPK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling
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