Retinoblastoma Binding Protein 8 Antikörper (AA 620-897)
Kurzübersicht für Retinoblastoma Binding Protein 8 Antikörper (AA 620-897) (ABIN2668263)
Target
Alle Retinoblastoma Binding Protein 8 (RBBP8) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 620-897
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Aufreinigung
- Protein A Chromatography
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Immunogen
- This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 μg/μL
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
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Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Antibodies in solution can be stored at -20 °C for 2 years.
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Haltbarkeit
- 6 months
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Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." in: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).
: "Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1." in: Oncotarget, Vol. 7, Issue 36, pp. 57679-57693, (2016) (PubMed).
: "Quantitation of DNA double-strand break resection intermediates in human cells." in: Nucleic acids research, Vol. 42, Issue 3, pp. e19, (2014) (PubMed).
: "Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection." in: Molecular cell, Vol. 54, Issue 6, pp. 1022-33, (2014) (PubMed).
: "An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway." in: Nature structural & molecular biology, Vol. 18, Issue 1, pp. 80-4, (2011) (PubMed).
: "BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP." in: Genes & development, Vol. 20, Issue 13, pp. 1721-6, (2006) (PubMed).
: "
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Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." in: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).
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- Retinoblastoma Binding Protein 8 (RBBP8)
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Andere Bezeichnung
- CtIP
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Molekulargewicht
- 120 kDa
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Gen-ID
- 5932
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Pathways
- Zellzyklus, DNA Reparatur
Target
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