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Retinoblastoma Binding Protein 8 Antikörper (AA 620-897)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Retinoblastoma Binding Protein 8 in WB, IP, ICC und IF. Er zeigt eine Reaktivität gegenüber Human und wurde in 6+ Publikationen erwähnt.
Produktnummer ABIN2668263

Kurzübersicht für Retinoblastoma Binding Protein 8 Antikörper (AA 620-897) (ABIN2668263)

Target

Alle Retinoblastoma Binding Protein 8 (RBBP8) Antikörper anzeigen
Retinoblastoma Binding Protein 8 (RBBP8)

Reaktivität

  • 54
  • 24
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 55
  • 2
Maus

Klonalität

  • 55
  • 2
Monoklonal

Konjugat

  • 41
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Retinoblastoma Binding Protein 8 Antikörper ist unkonjugiert

Applikation

  • 32
  • 23
  • 11
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon

14-1
  • Bindungsspezifität

    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 620-897

    Aufreinigung

    Protein A Chromatography

    Immunogen

    This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.

    Isotyp

    IgG1
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 μg/μL

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Antibodies in solution can be stored at -20 °C for 2 years.

    Haltbarkeit

    6 months
  • Onyango, Howard, Neherin, Yanez, Stark: "Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." in: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).

    Bakr, Köcher, Volquardsen, Petersen, Borgmann, Dikomey, Rothkamm, Mansour: "Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1." in: Oncotarget, Vol. 7, Issue 36, pp. 57679-57693, (2016) (PubMed).

    Zhou, Caron, Legube, Paull: "Quantitation of DNA double-strand break resection intermediates in human cells." in: Nucleic acids research, Vol. 42, Issue 3, pp. e19, (2014) (PubMed).

    Makharashvili, Tubbs, Yang, Wang, Barton, Zhou, Deshpande, Lee, Lobrich, Sleckman, Wu, Paull: "Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection." in: Molecular cell, Vol. 54, Issue 6, pp. 1022-33, (2014) (PubMed).

    Zhang, Jasin: "An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway." in: Nature structural & molecular biology, Vol. 18, Issue 1, pp. 80-4, (2011) (PubMed).

    Yu, Fu, Lai, Baer, Chen: "BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP." in: Genes & development, Vol. 20, Issue 13, pp. 1721-6, (2006) (PubMed).

  • Target

    Retinoblastoma Binding Protein 8 (RBBP8)

    Andere Bezeichnung

    CtIP

    Molekulargewicht

    120 kDa

    Gen-ID

    5932

    Pathways

    Zellzyklus, DNA Reparatur
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