Leptin Antikörper
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- Target Alle Leptin (LEP) Antikörper anzeigen
- Leptin (LEP)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Leptin Antikörper ist unkonjugiert
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Applikation
- Multiplex Assay (MA)
- Aufreinigung
- The antibody was purified by affinity chromatography.
- Klon
- M1905E01
- Isotyp
- IgG2a
- Top Product
- Discover our top product LEP Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- Leptin (LEP)
- Andere Bezeichnung
- Leptin (LEP Produkte)
- Synonyme
- ob antikoerper, obese antikoerper, LEPD antikoerper, OB antikoerper, OBS antikoerper, leptin antikoerper, Lep antikoerper, LEP antikoerper, lep antikoerper
- Hintergrund
- Leptin is primarily synthesized from adipocytes and plays a major role in energy homeostasis and obesity. Leptin resistance has been proposed as a pathophysiological mechanism of obesity. In obese individuals, expression of the short form of the leptin receptor, Ob-Ra, is downregulated, and the individual may be unresponsive to leptin signals. Leptin has also been implicated in the regulation of reproduction, glucose homeostasis, bone formation, hematopoiesis, and wound healing.
- Pathways
- JAK-STAT Signalweg, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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