CD25 Antikörper
Kurzübersicht für CD25 Antikörper (ABIN2664437)
Target
Alle CD25 (IL2RA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Pavian, Schimpanse, Cynomolgus, Rhesusaffen, Pigtailed Macaque
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Aufreinigung
- The antibody was purified by affinity chromatography.
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Isotyp
- IgG1 kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
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Andere Bezeichnung
- CD25
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Hintergrund
- CD25 is a 55 kD type I transmembrane glycoprotein also known as the low affinity IL-2 receptor α chain or Tac. It is expressed on progenitor lymphocytes, activated T and B cells, and activated monocytes/macrophages. CD25 is also expressed on a subset of non-stimulated CD4+ T cells termed T regulatory cells. CD25 associates with the IL-2 receptor β (CD122) and common γ chains (CD132) to form the high affinity IL-2R complex.
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Pathways
- JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation
Target
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