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PDGFRB Antikörper

PDGFRB Reaktivität: Maus FACS, IP Wirt: Ratte Monoclonal APB5 unconjugated
Produktnummer ABIN2664225
  • Target Alle PDGFRB Antikörper anzeigen
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    Reaktivität
    • 207
    • 86
    • 68
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 169
    • 41
    • 5
    • 3
    Ratte
    Klonalität
    • 160
    • 58
    Monoklonal
    Konjugat
    • 109
    • 11
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Dieser PDGFRB Antikörper ist unkonjugiert
    Applikation
    • 151
    • 71
    • 54
    • 53
    • 49
    • 29
    • 28
    • 26
    • 16
    • 11
    • 10
    • 9
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    APB5
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product PDGFRB Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    Andere Bezeichnung
    CD140b (PDGFRB Produkte)
    Hintergrund
    Platelet-derived growth factor receptor-β (PDGFR-β), CD140b, is one of two receptors for platelet-derived growth factors (PDGFs) and binds to all isoforms of PDGFs. PDGFRβ is a receptor tyrosine kinase that forms homodimers or heterodimers on the surface upon ligand binding and phosphorylates substrates. PDGFRs consist of either homodimers of α/α, β/β, or heterodimers of α/β. PDGF receptors, α and β, are single glycoproteins with intracellular tyrosine kinase domain. Their ligand, PDGF, is a mitogen for connective tissue and glial cells. CD140b is expressed on embryonic tissues and mesenchymal-derived cells adult mice. PDGF plays a role in wound healing and acts as a chemoattractant for fibroblasts, smooth muscle cells, glial cells, monocytes, and neutrophils.
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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