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PDGFRB Antikörper (Platelet Derived Growth Factor Receptor beta) N-Term Primary Antibody

PDGFRB Reaktivität: Human FACS, IF, IHC (p), WB Wirt: Kaninchen Polyclonal RB01554 unconjugated
Produktnummer ABIN392034
$412.50
Zzgl. Versandkosten $45.00
Lieferung in 10 bis 11 Werktagen
  • Target Alle PDGFRB Antikörper anzeigen
    PDGFRB
    Bindungsspezifität
    • 22
    • 22
    • 22
    • 16
    • 15
    • 11
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-72, N-Term
    Reaktivität
    • 216
    • 93
    • 84
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 196
    • 29
    • 3
    • 2
    Kaninchen
    Klonalität
    • 186
    • 44
    Polyklonal
    Konjugat
    • 118
    • 14
    • 9
    • 9
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Dieser PDGFRB Antikörper ist unkonjugiert
    Applikation
    • 136
    • 91
    • 64
    • 54
    • 53
    • 30
    • 29
    • 22
    • 16
    • 11
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PDGFRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-72 amino acids from the N-terminal region of human PDGFRB.
    Klon
    RB01554
    Isotyp
    Ig Fraction
  • Applikationshinweise
    IF: 1:10~50. IHC-P: 1:10~50. FC: 1:10~50. WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    PDGFRB
    Andere Bezeichnung
    PDGFRB (PDGFRB Produkte)
    Synonyme
    AI528809, CD140b, PDGFR-1, Pdgfr, CD140B, IBGC4, JTK12, PDGFR, PDGFR1, platelet derived growth factor receptor, beta polypeptide, platelet derived growth factor receptor beta, Pdgfrb, PDGFRB
    Hintergrund
    PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses the gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia.
    Molekulargewicht
    123968
    Gen-ID
    5159
    NCBI Accession
    NP_002600
    UniProt
    P09619
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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