PDGFRB Antikörper (AA 40-72)

Produktnummer ABIN3029811

Produktdetails anti-PDGFRB Antikörper

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Bindungsspezifität: AA 40-72

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDGFRB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Aufreinigung: Purified

Immunogen: A portion of amino acids 40-72 from the human protein was used as the immunogen for this CD140b / PDGFR beta antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the PDGFR beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50,Western blot: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C for up to one month. For long term, aliquot the PDGFR beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu PDGFRB

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Andere Bezeichnung: PDGFR beta (CD140b) (PDGFRB Produkte)

Synonyme: AI528809 antikoerper, CD140b antikoerper, PDGFR-1 antikoerper, Pdgfr antikoerper, CD140B antikoerper, IBGC4 antikoerper, JTK12 antikoerper, PDGFR antikoerper, PDGFR1 antikoerper, platelet derived growth factor receptor, beta polypeptide antikoerper, platelet derived growth factor receptor beta antikoerper, Pdgfrb antikoerper, PDGFRB antikoerper

Hintergrund: PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses the gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia.

UniProt: P09619

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling