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PDGFRB Antikörper (Platelet Derived Growth Factor Receptor beta) AA 40-72 Primary Antibody

PDGFRB Reaktivität: Human FACS, IF, IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3029811
$521.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle PDGFRB Antikörper anzeigen
    PDGFRB
    Bindungsspezifität
    • 22
    • 22
    • 22
    • 16
    • 15
    • 11
    • 9
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-72
    Reaktivität
    • 216
    • 93
    • 84
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 196
    • 29
    • 3
    • 2
    Kaninchen
    Klonalität
    • 186
    • 44
    Polyklonal
    Konjugat
    • 118
    • 14
    • 9
    • 9
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Dieser PDGFRB Antikörper ist unkonjugiert
    Applikation
    • 136
    • 90
    • 63
    • 54
    • 53
    • 31
    • 29
    • 22
    • 16
    • 11
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Aufreinigung
    Purified
    Immunogen
    A portion of amino acids 40-72 from the human protein was used as the immunogen for this CD140b / PDGFR beta antibody.
    Isotyp
    Ig Fraction
  • Applikationshinweise
    The stated application concentrations are suggested starting amounts. Titration of the PDGFR beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50,Western blot: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at 4°C for up to one month. For long term, aliquot the PDGFR beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    PDGFRB
    Andere Bezeichnung
    PDGFR beta (CD140b) (PDGFRB Produkte)
    Synonyme
    AI528809, CD140b, PDGFR-1, Pdgfr, CD140B, IBGC4, JTK12, PDGFR, PDGFR1, platelet derived growth factor receptor, beta polypeptide, platelet derived growth factor receptor beta, Pdgfrb, PDGFRB
    Hintergrund
    PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses the gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia.
    UniProt
    P09619
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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