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Caspase 1 Antikörper

CASP1 Reaktivität: Maus FACS Wirt: Ratte Monoclonal 5B10 unconjugated
Produktnummer ABIN2664090
  • Target Alle Caspase 1 (CASP1) Antikörper anzeigen
    Caspase 1 (CASP1)
    Reaktivität
    • 94
    • 35
    • 29
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 104
    • 11
    • 3
    • 1
    Ratte
    Klonalität
    • 95
    • 24
    Monoklonal
    Konjugat
    • 80
    • 18
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser Caspase 1 Antikörper ist unkonjugiert
    Applikation
    • 91
    • 47
    • 45
    • 24
    • 14
    • 14
    • 11
    • 6
    • 3
    • 3
    • 3
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    5B10
    Isotyp
    IgG2a
    Top Product
    Discover our top product CASP1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    Caspase 1 (CASP1)
    Andere Bezeichnung
    Caspase-1 (CASP1 Produkte)
    Synonyme
    ICE antikoerper, IL1BC antikoerper, P45 antikoerper, Il1bc antikoerper, Ice antikoerper, CASP1 antikoerper, CG5370 antikoerper, DCP-1 antikoerper, DCP1 antikoerper, Dcp1 antikoerper, Dmel\\CG5370 antikoerper, ccp1 antikoerper, dcp-1 antikoerper, dcp1 antikoerper, l(2)01862 antikoerper, l(2)02132 antikoerper, caspase 1 antikoerper, caspase 1, apoptosis-related cysteine peptidase antikoerper, caspase 4, apoptosis-related cysteine peptidase antikoerper, Death caspase-1 antikoerper, caspase-1 antikoerper, caspase antikoerper, caspase recruitment domain-containing protein 16 antikoerper, caspase 4 antikoerper, CASP1 antikoerper, Casp1 antikoerper, CASP4 antikoerper, Dcp-1 antikoerper, Caspase1 antikoerper, LOC5564196 antikoerper, LOC451519 antikoerper
    Hintergrund
    Caspase -1 plays a vital role in cleaving the inactive procytokine pro-IL-1 beta to generate the active 17 kd mature form of IL-1beta, a key mediator of inflammation. Active caspase-1 (ICE) is derived a single proenzyme of 45 Kd. An active ICE comprises two subunits of P20 and two subunits of P10 after removal a large amino-terminal pro-domain and a small linker peptide. Caspase-1 is reported to be involved in CD95- mediated apoptosis. Four alternatively spliced variants of caspase-1 have been reported, with mw ranging from 30-48 kd.
    Pathways
    Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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