The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
TEK antikoerper, DKFZp469E064 antikoerper, AA517024 antikoerper, Cd202b antikoerper, Hyk antikoerper, Tie2 antikoerper, tie-2 antikoerper, CD202B antikoerper, TIE-2 antikoerper, TIE2 antikoerper, VMCM antikoerper, VMCM1 antikoerper, Tie-2 antikoerper, tie2 antikoerper, TEK receptor tyrosine kinase antikoerper, angiopoietin-1 receptor antikoerper, TEK tyrosine kinase, endothelial antikoerper, TEK antikoerper, LOC100408334 antikoerper, tek antikoerper, Tek antikoerper
Hintergrund
CD202b is a 145 kD type I transmembrane protein, also known as Tie2 or TEK. It is a member of the receptor tyrosine kinase (RTK) family of proteins and is expressed by endothelial cells and their progenitors, quiescent hematopoietic stem cells (HSCs), and a subpopulation of monocytes. Angiopoietin-1 (Ang-1) is an activator of CD202b to promote, maintain, and stabilize mature vessels and to maintain HSCs in quiescent state. Ang-2 is another ligand of CD202b, which is involved in postnatal angiogenesis and in antagonizing the effects of Ang-1. Tie2 binds to Ang-4 as well.