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TEK Produkte

(TEK Tyrosine Kinase, Endothelial (TEK))
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations\; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq, Jul 2008].

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Ausgewählte TEK Kategorien

TEK Antikörper

High quality antibodies with extensive validation data.

TEK ELISA Kits

Reliable ELISA kits for a wide range of species.

TEK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene TEK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (5)
Kat. Nr. ABIN1327048
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC
Validierungen
  • (4)
Kat. Nr. ABIN7249630
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, FACS, ICC, Neut
Validierungen
  • (4)
Kat. Nr. ABIN7193241
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene TEK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (5)
Kat. Nr. ABIN6730884
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6959878
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6959877
Menge 96 tests
Datenblatt Datenblatt

Empfohlene TEK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect cells (Sf9)
Validierungen
  • (2)
Kat. Nr. ABIN5570126
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN6992355
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1322461
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren TEK Produkten

Idowu, Etzrodt, Seeliger, Bolanos-Palmieri, Thamm, Haller, David: "Identification of specific Tie2 cleavage sites and therapeutic modulation in experimental sepsis." in: eLife, Vol. 9, (2020) (PubMed).

Liu, Tang, Li, Pu, Yang, Chang: "PADI4 stimulates esophageal squamous cell carcinoma tumor growth and up-regulates CA9 expression." in: Molecular carcinogenesis, Vol. 58, Issue 1, pp. 66-75, (2019) (PubMed).

Shao, Sottoriva, Palasiewicz, Zhang, Hyun, Soni, Paik, Gao, Cuervo, Malik, Rehman, Lucas, Pajcini: "A Tie2-Notch1 signaling axis regulates regeneration of the endothelial bone marrow niche." in: Haematologica, (2019) (PubMed).

Guo, Si, Zhou, Wang, Zhang, Leung, Xu, Zhang: "Decreased PECAM1-mediated TGF-β1 expression in the mid-secretory endometrium in women with recurrent implantation failure." in: Human reproduction (Oxford, England), Vol. 33, Issue 5, pp. 832-843, (2018) (PubMed).

Triantafyllou, Pop, Possamai, Wilhelm, Liaskou, Singanayagam, Bernsmeier, Khamri, Petts, Dargue, Davies, Tickle, Yuksel, Patel, Abeles, Stamataki, Curbishley, Ma, Wilson, Coen, Woollard, Quaglia et al.: "MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure. ..." in: Gut, Vol. 67, Issue 2, pp. 333-347, (2018) (PubMed).

Higgins, De Ceunynck, Kellum, Chen, Gu, Chaudhry, Schulman, Libermann, Lu, Shapiro, Christiani, Flaumenhaft, Parikh: "Tie2 protects the vasculature against thrombus formation in systemic inflammation." in: The Journal of clinical investigation, Vol. 128, Issue 4, pp. 1471-1484, (2018) (PubMed).

Ko, Kim: "Cooperation between ZEB2 and Sp1 promotes cancer cell survival and angiogenesis during metastasis through induction of survivin and VEGF." in: Oncotarget, Vol. 9, Issue 1, pp. 726-742, (2018) (PubMed).

Kato, Diéguez-Hurtado, Park, Hong, Kato-Azuma, Adams, Stehling, Trappmann, Wrana, Koh, Adams: "Pulmonary pericytes regulate lung morphogenesis." in: Nature communications, Vol. 9, Issue 1, pp. 2448, (2018) (PubMed).

Lu, Tai, Ai, Gessler, Su, Yao, Zheng, Zamore, Xu, Gao: "Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs." in: Molecular therapy. Nucleic acids, Vol. 10, pp. 349-360, (2018) (PubMed).

Trieu, van Meurs, van Leeuwen, Van Slyke, Hoang, Geeraedts, Boer, van den Brom: "Vasculotide, an Angiopoietin-1 Mimetic, Restores Microcirculatory Perfusion and Microvascular Leakage and Decreases Fluid Resuscitation Requirements in Hemorrhagic Shock." in: Anesthesiology, Vol. 128, Issue 2, pp. 361-374, (2018) (PubMed).

Synonyme und alternative Namen zu TEK

TEK receptor tyrosine kinase (TEK), angiopoietin-1 receptor (LOC100408334), TEK receptor tyrosine kinase (tek), TEK receptor tyrosine kinase (Tek), TEK tyrosine kinase, endothelial (tek), AA517024, Cd202b, CD202B, DKFZp469E064, Hyk, TEK, tie-2, TIE-2, Tie-2, Tie2, TIE2, tie2, VMCM, VMCM1

Bezeichner auf Proteinebene für TEK

  • growth factor receptor Tie2/Tek
  • TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal)
  • Angiopoietin-1 receptor
  • TEK tyrosine kinase, endothelial
  • angiopoietin-1 receptor-like
  • STK1
  • angiopoietin-1 receptor
  • endothelial tyrosine kinase
  • mTIE2
  • p140 TEK
  • tunica interna endothelial cell kinase
  • tyrosine kinase with Ig and EGF homology domains-2
  • tyrosine-protein kinase receptor TEK
  • tyrosine-protein kinase receptor TIE-2
  • hTIE2
  • soluble TIE2 variant 1
  • soluble TIE2 variant 2
  • protein-tyrosine kinase Tie2
  • endothelial-specific receptor tyrosine kinase
  • tyrosine kinases that contain immunoglobulin-like loops and epidermal growth factor-similar domains 2
  • endothelium-specific receptor tyrosine kinase 2
  • tyrosine-protein kinase receptor Tie-2
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