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CD25 Antikörper (Biotin)

Name: CD25 Antikörper (Biotin)
SKU: ABIN2661002
Price: 203.43 EUR
Availability: InStock

IL2RA Reaktivität: Ratte FACS Wirt: Maus Monoclonal OX-39 Biotin

FACS

1 image

Produktnummer ABIN2661002

Datenblatt (PDF)

Target Alle CD25 (IL2RA) Antikörper anzeigen

CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
Reaktivität
184

137

40

10

10

5

3

3

2

2

1

1
Ratte
Wirt
159

103

80

2

2

1

1
Maus
Passende Sekundärantikörper
Klonalität
272

70

4
Monoklonal
Konjugat
128

36

32

26

24

13

8

7

4

4

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD25 Antikörper ist konjugiert mit Biotin
Applikation
247

92

60

59

52

44

26

19

15

13

10

9

9

8

6

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Aufreinigung

The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Klon

OX-39

Isotyp

IgG1 kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.5 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

The antibody solution should be stored undiluted between 2°C and 8°C.
Target

CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Andere Bezeichnung

CD25 (IL2RA Produkte)

Hintergrund

CD25 is a 55 kD glycoprotein also known as IL-2 receptor α chain. It is broadly expressed on activated T and B cells, a subset of thymic and splenic dendritic cells, and intestinal epithelial cells in the rat. IL-2 is a critical cytokine involved in lymphocyte proliferation and clonal expansion. IL-2 signaling requires the high affinity IL-2 receptor composed of IL-2 receptor chains α, β, and γ. The OX-39 antibody weakly inhibits IL-2 binding to the IL-2 receptor and has been shown to block some IL-2 mediated responses in vitro.

Pathways

JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation