GLI1 Antikörper

Produktnummer ABIN265275

Dieses Anti-GLI1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GLI1 in WB. Geeignet für Human.

Kurzübersicht für GLI1 Antikörper (ABIN265275)

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GLI1 Antikörper

Spezifität: Thia antibody detects Zinc Finger Protein GLI1, found in testis, myometrium and fallopian tube.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from human zinc finger protein GLI1

Anwendungsinformationen

Applikationshinweise: Western blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Details zu GLI1

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Andere Bezeichnung: GLI1

Hintergrund: Zinc Finger Protein GLI1 is a member of the Kruppel family of zinc finger proteins. It is thought that it may regulate the transcription of specific genes dring normal development and may play a role in craniofacial development and digital development. It also may be involved in the development of the central nervous system and gastrointestinal tract. This protein mediates SHH signaling and thus cell proliferation and differentiation. It has been localized to the cytoplasm and nucleus. It is tethered in the cytoplasm by binding to SUFU and activation and translocalization to the nucleus is promoted by interation with STK36. Protein expression is amplified in glioblastoma cells. Defects in the GLI1 protein may be a cause of breast cancer.Synonyms: GLI, GLI-1, Glioma-associated oncogene, Oncogene GLI, Zinc finger protein GLI1

Gen-ID: 2735

NCBI Accession: NP_001153517

UniProt: P08151

Pathways: Hedgehog Signalweg, Dopaminergic Neurogenesis