Prothrombin Antikörper

Produktnummer ABIN264058

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Prothrombin in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Prothrombin Antikörper (ABIN264058)

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Prothrombin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: BDI095

Produktdetails anti-Prothrombin Antikörper

Spezifität: This antibody binds Prothrombin, Prethrombin 1 and fragment 2 (residues 156-271) in solid-phase ELISA. Blots Human Prothrombin in Western blot.

Produktmerkmale: Synonyms: Coagulation factor II

Aufreinigung: Gel filtration and Ion Exchange Chromatography

Immunogen: Purified Human Prothrombin

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot. A starting range of 1-5g/mL is recommended.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with distilled water

Konzentration: 1.0 mg/mL (prior to lyophilization)

Buffer: 10 mM Sodium phosphate, 0.15 M Sodium Chloride, pH 7.4 containing 0.01 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at -20 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one monthor (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Prothrombin

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Andere Bezeichnung: Prothrombin (F2)

Hintergrund: Prothrombin (Factor 2 in the coagulation cascade) is proteolytically cleaved at two sites by Factor Xa to form thrombin (Factor IIa) in an important step of the coagulation cascade which ultimately results in the stemming of blood loss. Thrombin being the single most important constituent of the coagulation cascade in terms of its feedback activation roles. Prothrombin also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in Prothrombin lead to various forms of thrombosis and dysprothrombinemia.Synonyms: Coagulation factor II

Gen-ID: 2147

UniProt: P00734

Pathways: Komplementsystem, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling