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CD25 Antikörper

IL2RA Reaktivität: Maus FACS, IHC, IP, Func Wirt: Ratte Monoclonal PC61-5 unconjugated

Produktnummer ABIN2567370

Datenblatt (PDF)

Target Alle CD25 (IL2RA) Antikörper anzeigen

CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
Reaktivität
181

131

40

10

10

5

3

3

2

2

1

1
Maus
Wirt
158

97

80

2

1

1
Ratte
Passende Sekundärantikörper
Klonalität
263

70

4
Monoklonal
Konjugat
124

36

32

27

25

13

8

7

4

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD25 Antikörper ist unkonjugiert
Applikation
240

92

60

57

52

48

26

19

15

13

10

9

9

8

6

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Functional Studies (Func)

Spezifität

The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor α chain (IL-2R α), expressed on early progenitors of T and B lineage, and on B and T cells.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Klon

PC61-5

Isotyp

IgG1 lambda

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

2 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C. Do not freeze.
Target

CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))

Andere Bezeichnung

CD25 (IL2RA Produkte)

Hintergrund

The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor α chain (IL-2R α), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor β) and CD 132 (IL-2 Receptor γc, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2Rα. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation.The PC61.5 antibody block the binding of IL-2 to both high-affinity and low-affinity receptors.

Gen-ID

16184

UniProt

P01590

Pathways

JAK-STAT Signalweg, Growth Factor Binding, Activated T Cell Proliferation