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PARP1 Antikörper

PARP1 Reaktivität: Human, Maus, Ratte, Drosophila melanogaster, Hamster, Xenopus laevis WB, ELISA, IP, IF, IHC (p), IHC (fro) Wirt: Maus Monoclonal A6-4-12 unconjugated
Produktnummer ABIN2476185
  • Target Alle PARP1 Antikörper anzeigen
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    Reaktivität
    • 223
    • 58
    • 43
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Drosophila melanogaster, Hamster, Xenopus laevis
    Wirt
    • 213
    • 27
    • 1
    Maus
    Klonalität
    • 206
    • 35
    Monoklonal
    Konjugat
    • 138
    • 16
    • 15
    • 13
    • 12
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PARP1 Antikörper ist unkonjugiert
    Applikation
    • 150
    • 117
    • 69
    • 36
    • 31
    • 26
    • 24
    • 23
    • 22
    • 17
    • 16
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Fruchtfliege (Drosophila melanogaster), Hamster, Maus, Ratte (Rattus), Xenopus laevis
    Produktmerkmale
    Purified IgG
    Aufreinigung
    Purified
    Klon
    A6-4-12
    Isotyp
    IgG1
    Top Product
    Discover our top product PARP1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
  • Pinton, Manente, Murer, De Marino, Mutti, Moro: "PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1." in: Journal of cellular and molecular medicine, Vol. 17, Issue 2, pp. 233-41, (2013) (PubMed).

    Harris, Jakob, Taucher-Scholz, Dianov, Becherel, Lavin: "Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage." in: Human molecular genetics, Vol. 18, Issue 21, pp. 4102-17, (2009) (PubMed).

    Freire, dAdda Di Fagagna, Wu, Pedrazzi, Stagljar, Hickson, Jackson: "Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha." in: Nucleic acids research, Vol. 29, Issue 15, pp. 3172-80, (2001) (PubMed).

  • Target
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    Andere Bezeichnung
    POLY(ADP-RIBOSE) POLYMERASE-1 (PARP1 Produkte)
    Gen-ID
    142
    UniProt
    P09874
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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