PARP1 Antikörper
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- Target Alle PARP1 Antikörper anzeigen
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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Reaktivität
- Human, Maus, Ratte, Drosophila melanogaster, Hamster, Xenopus laevis
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PARP1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Fruchtfliege (Drosophila melanogaster), Hamster, Maus, Ratte (Rattus), Xenopus laevis
- Produktmerkmale
- Purified IgG
- Aufreinigung
- Purified
- Klon
- A6-4-12
- Isotyp
- IgG1
- Top Product
- Discover our top product PARP1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/mL
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PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1." in: Journal of cellular and molecular medicine, Vol. 17, Issue 2, pp. 233-41, (2013) (PubMed).
: "Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage." in: Human molecular genetics, Vol. 18, Issue 21, pp. 4102-17, (2009) (PubMed).
: "Cleavage of the Bloom's syndrome gene product during apoptosis by caspase-3 results in an impaired interaction with topoisomerase IIIalpha." in: Nucleic acids research, Vol. 29, Issue 15, pp. 3172-80, (2001) (PubMed).
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PARP1 inhibition affects pleural mesothelioma cell viability and uncouples AKT/mTOR axis via SIRT1." in: Journal of cellular and molecular medicine, Vol. 17, Issue 2, pp. 233-41, (2013) (PubMed).
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- Target
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
- Andere Bezeichnung
- POLY(ADP-RIBOSE) POLYMERASE-1 (PARP1 Produkte)
- Gen-ID
- 142
- UniProt
- P09874
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, DNA Reparatur, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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