CDK2 Antikörper
Kurzübersicht für CDK2 Antikörper (ABIN2470565)
Target
Alle CDK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Recognizes cdk2, Mr 33kD. Does not cross-react with other cdks.
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Aufreinigung
- Protein G Column
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Immunogen
- CDK2 monoclonal antibody was raised against recombinant CDK2 (Human).
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Isotyp
- IgG
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Applikationshinweise
- CDK2 antibody can be used in immunohistochemistry starting at 10 μg/mL.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05 % sodium azide, before the addition of glycerol to 30 %
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- As with all antibodies avoid freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store CDK2 antibody at 4 °C or -20 °C.
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- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
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Andere Bezeichnung
- CDK2
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Hintergrund
- Cyclin-dependent kinase 2 (CDK2), a CDC2/CDK-type protein kinase, regulates cell-cycle transition from G1 to S phase. CDK2 activation requires formation of a heterodimer with cyclin A, D, or E and phosphorylation by CAK. CDK2 inhibition results from association with p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Two alternatively spliced variants and multiple transcription initiation sites have been reported. Inhibition of CDK2 has been suggested to help prevent chemotherapy-induced alopecia in cancer patients.
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Gen-ID
- 1017
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UniProt
- P24941
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Pathways
- PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
Target
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