Der Maus Monoklonal Anti-CDK2-Antikörper wurde für WB, IHC, ELISA und IP validiert. Er ist geeignet, CDK2 in Proben von Human, Maus und Xenopus laevis zu detektieren.
CDK2 antibody can be used in immunohistochemistry starting at 10 μg/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05 % sodium azide, before the addition of glycerol to 30 %
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
As with all antibodies avoid freeze/thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store CDK2 antibody at 4 °C or -20 °C.
Target
CDK2
(Cyclin-Dependent Kinase 2 (CDK2))
Andere Bezeichnung
CDK2
Hintergrund
Cyclin-dependent kinase 2 (CDK2), a CDC2/CDK-type protein kinase, regulates cell-cycle transition from G1 to S phase. CDK2 activation requires formation of a heterodimer with cyclin A, D, or E and phosphorylation by CAK. CDK2 inhibition results from association with p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Two alternatively spliced variants and multiple transcription initiation sites have been reported. Inhibition of CDK2 has been suggested to help prevent chemotherapy-induced alopecia in cancer patients.