PCNA Antikörper (Internal Region)

Produktnummer ABIN2470261

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PCNA in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Huhn, Affe, Hund, Rind (Kuh), Xenopus laevis und Fisch.

Kurzübersicht für PCNA Antikörper (Internal Region) (ABIN2470261)

Target: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Reaktivität: Human, Maus, Ratte, Huhn, Affe, Hund, Rind (Kuh), Xenopus laevis, Fisch

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCNA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-PCNA Antikörper

Bindungsspezifität: Internal Region

Aufreinigung: Immunoaffinity Chromatography

Immunogen: PCNA antibody was raised against an internal region of PCNA (Human).

Anwendungsinformationen

Applikationshinweise: PCNA antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store PCNA antibody at 4 °C or -20 °C.

Details zu PCNA

Target: PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Andere Bezeichnung: PCNA

Hintergrund: The proliferating cell nuclear antigen (PCNA) is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the processibility of DNA polymerase during elongation of the leading strand. PCNA is expressed in the nucleus of all proliferating cells and is pivotal for DNA synthesis and cell cycle progression. In response to DNA damage, PCNA is mono-ubiquitinated and is involved in mismatch-provoked excision. PCNA is a useful marker for DNA synthesis and is highly conserved among most species.

Gen-ID: 5111

UniProt: P12004

Pathways: Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagie