Cyclin A1 Antikörper (full length)

Produktnummer ABIN2470210

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cyclin A1 in WB, ELISA, IHC, IF und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Cyclin A1 Antikörper (full length) (ABIN2470210)

Target: Cyclin A1 (CCNA1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-Cyclin A1 Antikörper

Bindungsspezifität: full length

Aufreinigung: Delipidation and Defibrination

Immunogen: Full length synthetic polypeptide corresponding to the human gene sequence.

Anwendungsinformationen

Applikationshinweise: Cyclin A1 antibody can be used in ELISA, and immunohistochemistry starting at 10 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01 % Sodium azide

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store Cyclin A1 antibody at 4 °C or -20 °C.

Details zu Cyclin A1

Target: Cyclin A1 (CCNA1)

Andere Bezeichnung: Cyclin A1

Hintergrund: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Gen-ID: 8900

UniProt: P78396

Pathways: Apoptose, Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA