Connexin 43/GJA1 Antikörper (C-Term)

Produktnummer ABIN2469543

Dieses Anti-Connexin 43/GJA1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Connexin 43/GJA1 in IHC. Geeignet für Human, Ratte, Maus, Hund, Rind (Kuh), Affe, Kaninchen, Meerschweinchen, Schwein, Hamster, Gibbon und Gorilla.

Kurzübersicht für Connexin 43/GJA1 Antikörper (C-Term) (ABIN2469543)

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Affe, Kaninchen, Meerschweinchen, Schwein, Hamster, Gibbon, Gorilla

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Connexin 43/GJA1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-Connexin 43/GJA1 Antikörper

Bindungsspezifität: C-Term

Spezifität: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: GJA1 antibody was raised against a peptide located in the C-Terminal domain of GJA1 (Human).

Anwendungsinformationen

Applikationshinweise: GJA1 antibody can be used in ELISA, Western Blot starting at 1 - 2 μg/mL, immunohistochemistry starting at 10 μg/mL, immunocytochemistry, immunoprecipitation starting at 1 - 2 μg/mL, and flow cytometry starting at 1 - 2 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies avoid freeze/thaw cycles.

Lagerung: 4 °C/-80 °C

Informationen zur Lagerung: GJA1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Details zu Connexin 43/GJA1

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Andere Bezeichnung: GJA1

Hintergrund: Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.

Gen-ID: 2697

UniProt: P17302

Pathways: MAPK Signalweg, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization